Tandem duplication PCR: an ultra-sensitive assay for the detection of internal tandem duplications of the FLT3 gene

Internal tandem duplication (ITD) mutations of the FLT3 gene have been associated with a poor prognosis in acute myeloid leukemia (AML). Detection of ITD-positive minor clones at the initial diagnosis and during the minimal residual disease (MRD) stage may be essential. We previously designed a delt...

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Bibliographic Details
Main Authors: Lin, Ming-Tseh, Tseng, Li-Hui, Beierl, Katie, Hsieh, Antony, Thiess, Michele, Chase, Nadine, Stafford, Amanda, Levis, Mark J., Eshleman, James R., Gocke, Christopher D.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744591/
https://ncbi.nlm.nih.gov/pubmed/23846441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PDM.0b013e31828308a1
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