Improved FLT3/ITD PCR assay predicts outcome following allogeneic transplant for AML

Acute myeloid leukemia (AML) patients harboring internal tandem duplication (ITD) mutations of the FMS-like tyrosine kinase 3 (FLT3) gene carry a poor prognosis. While allogeneic transplantation may improve outcomes, relapse occurs frequently. The FLT3/ITD mutation has been deemed an unsuitable mini...

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Bibliografski detalji
Izdano u:Biol Blood Marrow Transplant
Glavni autori: Grunwald, Michael R., Tseng, Li-Hui, Lin, Ming-Tseh, Pratz, Keith W., Eshleman, James R., Levis, Mark J., Gocke, Christopher D.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253693/
https://ncbi.nlm.nih.gov/pubmed/25240816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2014.08.015
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