Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy

Previous attempts to identify neuroprotective targets by studying the ischemic cascade and devising ways to suppress it have failed to translate to efficacious therapies for acute ischemic stroke(1). We hypothesized that studying the molecular determinants of endogenous neuroprotection in two well-e...

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Autori principali: Papadakis, Michalis, Hadley, Gina, Xilouri, Maria, Hoyte, Lisa C., Nagel, Simon, McMenamin, M Mary, Tsaknakis, Grigorios, Watt, Suzanne M., Drakesmith, Cynthia Wright, Chen, Ruoli, Wood, Matthew J A, Zhao, Zonghang, Kessler, Benedikt, Vekrellis, Kostas, Buchan, Alastair M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744134/
https://ncbi.nlm.nih.gov/pubmed/23435171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3097
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