Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy

Previous attempts to identify neuroprotective targets by studying the ischemic cascade and devising ways to suppress it have failed to translate to efficacious therapies for acute ischemic stroke(1). We hypothesized that studying the molecular determinants of endogenous neuroprotection in two well-e...

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Bibliografische gegevens
Hoofdauteurs: Papadakis, Michalis, Hadley, Gina, Xilouri, Maria, Hoyte, Lisa C., Nagel, Simon, McMenamin, M Mary, Tsaknakis, Grigorios, Watt, Suzanne M., Drakesmith, Cynthia Wright, Chen, Ruoli, Wood, Matthew J A, Zhao, Zonghang, Kessler, Benedikt, Vekrellis, Kostas, Buchan, Alastair M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744134/
https://ncbi.nlm.nih.gov/pubmed/23435171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3097
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