Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy

Previous attempts to identify neuroprotective targets by studying the ischemic cascade and devising ways to suppress it have failed to translate to efficacious therapies for acute ischemic stroke(1). We hypothesized that studying the molecular determinants of endogenous neuroprotection in two well-e...

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Main Authors: Papadakis, Michalis, Hadley, Gina, Xilouri, Maria, Hoyte, Lisa C., Nagel, Simon, McMenamin, M Mary, Tsaknakis, Grigorios, Watt, Suzanne M., Drakesmith, Cynthia Wright, Chen, Ruoli, Wood, Matthew J A, Zhao, Zonghang, Kessler, Benedikt, Vekrellis, Kostas, Buchan, Alastair M.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744134/
https://ncbi.nlm.nih.gov/pubmed/23435171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3097
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