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Cdk5 and the non-catalytic arrest of the neuronal cell cycle

Cyclin-dependent kinase 5 (Cdk5) is a nontraditional Cdk that is primarily active in postmitotic neurons. An important core function of Cdk5 involves regulating the migration and maturation of embryonic post-mitotic neurons. These developmental roles are dependent on its kinase activity. Initially,...

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Autors principals: Zhang, Jie, Herrup, Karl
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743047/
https://ncbi.nlm.nih.gov/pubmed/19001851
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