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Cdk5 Levels Oscillate during the Neuronal Cell Cycle: Cdh1 UBIQUITINATION TRIGGERS PROTEOSOME-DEPENDENT DEGRADATION DURING S-PHASE

When cell cycle re-activation occurs in post-mitotic neurons it places them at increased risk for death. The cell cycle/cell death association has been reported in many neurodegenerative diseases including Alzheimer disease (AD), yet the mechanisms by which a normal neuron suppresses the cycle remai...

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Autors principals: Zhang, Jie, Li, Huifang, Zhou, Tingwen, Zhou, Jiechao, Herrup, Karl
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406682/
https://ncbi.nlm.nih.gov/pubmed/22654103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.343152
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