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Cdk5 Suppresses the Neuronal Cell Cycle by Disrupting the E2F1–DP1 Complex

Neurons that reenter a cell cycle after maturation are at increased risk for death, yet the mechanisms by which a normal neuron suppresses the cycle remain mostly unknown. Our laboratory has shown that cyclin-dependent kinase 5 (Cdk5) is a potent cell cycle suppressor, and we report here on the mole...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Jie, Li, Huifang, Yabut, Odessa, Fitzpatrick, Haley, D'Arcangelo, Gabriella, Herrup, Karl
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862267/
https://ncbi.nlm.nih.gov/pubmed/20392944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5628-09.2010
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