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Cdk5 Suppresses the Neuronal Cell Cycle by Disrupting the E2F1–DP1 Complex
Neurons that reenter a cell cycle after maturation are at increased risk for death, yet the mechanisms by which a normal neuron suppresses the cycle remain mostly unknown. Our laboratory has shown that cyclin-dependent kinase 5 (Cdk5) is a potent cell cycle suppressor, and we report here on the mole...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862267/ https://ncbi.nlm.nih.gov/pubmed/20392944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5628-09.2010 |
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