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Dyrk1A Overexpression Inhibits Proliferation and Induces Premature Neuronal Differentiation of Neural Progenitor Cells

Dyrk1A is a member of the mammalian Dyrk [dual-specificity tyrosine-(Y)-phosphorylation regulated kinase] family of protein kinases that is expressed at high levels in the brain, but its role in the development and function of this organ is not well understood. The human DYRK1A gene is located on tr...

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Detalhes bibliográficos
Main Authors: Yabut, Odessa, Domogauer, Jason, D'Arcangelo, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842457/
https://ncbi.nlm.nih.gov/pubmed/20237271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4711-09.2010
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