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Dyrk1A Overexpression Inhibits Proliferation and Induces Premature Neuronal Differentiation of Neural Progenitor Cells

Dyrk1A is a member of the mammalian Dyrk [dual-specificity tyrosine-(Y)-phosphorylation regulated kinase] family of protein kinases that is expressed at high levels in the brain, but its role in the development and function of this organ is not well understood. The human DYRK1A gene is located on tr...

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Bibliographic Details
Main Authors: Yabut, Odessa, Domogauer, Jason, D'Arcangelo, Gabriella
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842457/
https://ncbi.nlm.nih.gov/pubmed/20237271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4711-09.2010
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