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Dyrk1A Overexpression Inhibits Proliferation and Induces Premature Neuronal Differentiation of Neural Progenitor Cells

Dyrk1A is a member of the mammalian Dyrk [dual-specificity tyrosine-(Y)-phosphorylation regulated kinase] family of protein kinases that is expressed at high levels in the brain, but its role in the development and function of this organ is not well understood. The human DYRK1A gene is located on tr...

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מידע ביבליוגרפי
Main Authors: Yabut, Odessa, Domogauer, Jason, D'Arcangelo, Gabriella
פורמט: Artigo
שפה:Inglês
יצא לאור: Society for Neuroscience 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842457/
https://ncbi.nlm.nih.gov/pubmed/20237271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4711-09.2010
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