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Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells

It has become apparent that chromatin modification plays a critical role in the regulation of cell-type-specific gene expression. Here, we show that an inhibitor of histone deacetylase, valproic acid (VPA), induced neuronal differentiation of adult hippocampal neural progenitors. In addition, VPA in...

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Detalhes bibliográficos
Main Authors: Hsieh, Jenny, Nakashima, Kinichi, Kuwabara, Tomoko, Mejia, Eunice, Gage, Fred H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC527137/
https://ncbi.nlm.nih.gov/pubmed/15537713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407643101
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