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Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development

The molecular mechanism by which neural progenitor cells commit to a specified lineage of the central nervous system remains unknown. We show that HDAC1 and HDAC2 redundantly control neuronal development and are required for neuronal specification. Mice lacking HDAC1 or HDAC2 in neuronal precursors...

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Detalles Bibliográficos
Main Authors: Montgomery, Rusty L., Hsieh, Jenny, Barbosa, Ana C., Richardson, James A., Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683090/
https://ncbi.nlm.nih.gov/pubmed/19380719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902750106
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