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Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development

The molecular mechanism by which neural progenitor cells commit to a specified lineage of the central nervous system remains unknown. We show that HDAC1 and HDAC2 redundantly control neuronal development and are required for neuronal specification. Mice lacking HDAC1 or HDAC2 in neuronal precursors...

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Bibliografske podrobnosti
Main Authors: Montgomery, Rusty L., Hsieh, Jenny, Barbosa, Ana C., Richardson, James A., Olson, Eric N.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683090/
https://ncbi.nlm.nih.gov/pubmed/19380719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902750106
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