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Epigenetic control of skull morphogenesis by histone deacetylase 8

Histone deacetylases (Hdacs) are transcriptional repressors with crucial roles in mammalian development. Here we provide evidence that Hdac8 specifically controls patterning of the skull by repressing a subset of transcription factors in cranial neural crest cells. Global deletion of Hdac8 in mice l...

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Autors principals: Haberland, Michael, Mokalled, Mayssa H., Montgomery, Rusty L., Olson, Eric N.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714711/
https://ncbi.nlm.nih.gov/pubmed/19605684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1809209
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