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Epigenetic control of skull morphogenesis by histone deacetylase 8
Histone deacetylases (Hdacs) are transcriptional repressors with crucial roles in mammalian development. Here we provide evidence that Hdac8 specifically controls patterning of the skull by repressing a subset of transcription factors in cranial neural crest cells. Global deletion of Hdac8 in mice l...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714711/ https://ncbi.nlm.nih.gov/pubmed/19605684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1809209 |
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