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The many roles of histone deacetylases in development and physiology: implications for disease and therapy

Histone deacetylases (HDACs) are part of a vast family of enzymes that have crucial roles in numerous biological processes, largely through their repressive influence on transcription. The expression of many HDAC isoforms in eukaryotic cells raises questions about their possible specificity or redun...

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Detalhes bibliográficos
Main Authors: Haberland, Michael, Montgomery, Rusty L., Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215088/
https://ncbi.nlm.nih.gov/pubmed/19065135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg2485
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