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Cyclin-Dependent Kinase 5 Is Essential for Neuronal Cell Cycle Arrest and Differentiation

Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase with significant homology to cell cycle-related Cdks but is not believed to be active in a typical cell cycle. In Cdk5-deficient embryos and Cdk5 chimeras, migration and survival of postmitotic neurons is compromised in a cell-autonomous...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Cicero, Samantha, Herrup, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725732/
https://ncbi.nlm.nih.gov/pubmed/16237170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1773-05.2005
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