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Functions of Huntingtin in Germ Layer Specification and Organogenesis

Huntington’s disease (HD) is a neurodegenerative disease caused by abnormal polyglutamine expansion in the huntingtin protein (Htt). Although both Htt and the HD pathogenic mutation (mHtt) are implicated in early developmental events, their individual involvement has not been adequately explored. In...

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Bibliografische gegevens
Hoofdauteurs: Nguyen, Giang D., Molero, Aldrin E., Gokhan, Solen, Mehler, Mark F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742581/
https://ncbi.nlm.nih.gov/pubmed/23967334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072698
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