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C-Terminal Complexin Sequence Is Selectively Required for Clamping and Priming But Not for Ca(2+) Triggering of Synaptic Exocytosis

Complexins are small soluble proteins that bind to assembling SNARE complexes during synaptic vesicle exocytosis, which in turn mediates neurotransmitter release. Complexins are required for clamping of spontaneous “mini ” release and for the priming and synaptotagmin-dependent Ca(2+) triggering of...

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Hlavní autoři: Kaeser-Woo, Yea Jin, Yang, Xiaofei, Südhof, Thomas C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742123/
https://ncbi.nlm.nih.gov/pubmed/22357870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3360-11.2012
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