Complexin II plays a positive role in Ca(2+)-triggered exocytosis by facilitating vesicle priming

SNARE-mediated exocytosis is a multistage process central to synaptic transmission and hormone release. Complexins (CPXs) are small proteins that bind very rapidly and with a high affinity to the SNARE core complex, where they have been proposed recently to inhibit exocytosis by clamping the complex...

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Bibliografiske detaljer
Main Authors: Cai, Haijiang, Reim, Kerstin, Varoqueaux, Frederique, Tapechum, Sompol, Hill, Kerstin, Sørensen, Jakob B., Brose, Nils, Chow, Robert H.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614796/
https://ncbi.nlm.nih.gov/pubmed/19033464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810232105
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