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C-Terminal Complexin Sequence Is Selectively Required for Clamping and Priming But Not for Ca(2+) Triggering of Synaptic Exocytosis

Complexins are small soluble proteins that bind to assembling SNARE complexes during synaptic vesicle exocytosis, which in turn mediates neurotransmitter release. Complexins are required for clamping of spontaneous “mini ” release and for the priming and synaptotagmin-dependent Ca(2+) triggering of...

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Bibliografiske detaljer
Main Authors: Kaeser-Woo, Yea Jin, Yang, Xiaofei, Südhof, Thomas C.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742123/
https://ncbi.nlm.nih.gov/pubmed/22357870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3360-11.2012
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