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Deconstructing complexin function in activating and clamping Ca(2+)-triggered exocytosis by comparing knockout and knockdown phenotypes
Complexin, a presynaptic protein that avidly binds to assembled SNARE complexes, is widely acknowledged to activate Ca(2+)-triggered exocytosis. In addition, studies of invertebrate complexin mutants and of mouse neurons with a double knockdown (DKD) of complexin-1 and -2 suggested that complexin ma...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3870694/ https://ncbi.nlm.nih.gov/pubmed/24297916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321367110 |
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