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Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation
We used resequencing and genotyping in African Americans with sickle cell anemia (SCA) to characterize associations with fetal hemoglobin (HbF) levels at the BCL11A, HBS1L-MYB and β-globin loci. Fine-mapping of HbF association signals at these loci confirmed seven SNPs with independent effects and i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740938/ https://ncbi.nlm.nih.gov/pubmed/21057501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.707 |
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