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The Switch from Fetal to Adult Hemoglobin

The fetal-to-adult hemoglobin switch and silencing of fetal hemoglobin (HbF) have been areas of long-standing interest among hematologists, given the fact that clinical induction of HbF production holds tremendous promise to ameliorate the clinical symptoms of sickle cell disease (SCD) and β-thalass...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sankaran, Vijay G., Orkin, Stuart H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530042/
https://ncbi.nlm.nih.gov/pubmed/23209159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a011643
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