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Switching from fetal to adult hemoglobin
The switch from fetal to adult hemoglobin relies on repression or silencing of the upstream γ-globin gene, but identification of the transcriptional repressors that bind to the sites at which a cluster of naturally occurring variants associated with HPFH (hereditary persistence of fetal hemoglobin)...
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| Publicado en: | Nat Genet |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6419756/ https://ncbi.nlm.nih.gov/pubmed/29610477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0094-z |
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