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Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities

In humans, embryonic, fetal, and adult hemoglobins are sequentially expressed in developing erythroblasts during ontogeny. For the past 40 years, this process has been the subject of intensive study because of its value to enlighten the biology of developmental gene regulation and because fetal hemo...

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Autors principals: Wilber, Andrew, Nienhuis, Arthur W., Persons, Derek A.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087525/
https://ncbi.nlm.nih.gov/pubmed/21321359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-316893
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