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Control of fetal hemoglobin: new insights emerging from genomics and clinical implications

Increased levels of fetal hemoglobin (HbF, α(2)γ(2)) are of no consequence in healthy adults, but confer major clinical benefits in patients with sickle cell anemia (SCA) and β thalassemia, diseases that represent major public health problems. Inter-individual HbF variation is largely genetically co...

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Detalhes bibliográficos
Main Authors: Thein, Swee Lay, Menzel, Stephan, Lathrop, Mark, Garner, Chad
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758709/
https://ncbi.nlm.nih.gov/pubmed/19808799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp401
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