Genome Wide Association Study of Fetal Hemoglobin in Sickle Cell Anemia in Tanzania

BACKGROUND: Fetal hemoglobin (HbF) is an important modulator of sickle cell disease (SCD). HbF has previously been shown to be affected by variants at three loci on chromosomes 2, 6 and 11, but it is likely that additional loci remain to be discovered. METHODS AND FINDINGS: We conducted a genome-wid...

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Udgivet i:PLoS One
Main Authors: Mtatiro, Siana Nkya, Singh, Tarjinder, Rooks, Helen, Mgaya, Josephine, Mariki, Harvest, Soka, Deogratius, Mmbando, Bruno, Msaki, Evarist, Kolder, Iris, Thein, Swee Lay, Menzel, Stephan, Cox, Sharon E., Makani, Julie, Barrett, Jeffrey C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221031/
https://ncbi.nlm.nih.gov/pubmed/25372704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111464
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