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Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation

We used resequencing and genotyping in African Americans with sickle cell anemia (SCA) to characterize associations with fetal hemoglobin (HbF) levels at the BCL11A, HBS1L-MYB and β-globin loci. Fine-mapping of HbF association signals at these loci confirmed seven SNPs with independent effects and i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Galarneau, Geneviève, Palmer, Cameron D, Sankaran, Vijay G, Orkin, Stuart H, Hirschhorn, Joel N, Lettre, Guillaume
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740938/
https://ncbi.nlm.nih.gov/pubmed/21057501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.707
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