A Functional Element Necessary for Fetal Hemoglobin Silencing

BACKGROUND: An improved understanding of the regulation of the fetal hemoglobin genes holds promise for the development of targeted therapeutic approaches for fetal hemoglobin induction in the β-hemoglobinopathies. Although recent studies have uncovered trans-acting factors necessary for this regula...

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Main Authors: Sankaran, Vijay G., Xu, Jian, Byron, Rachel, Greisman, Harvey A., Fisher, Chris, Weatherall, David J., Sabath, Daniel E., Groudine, Mark, Orkin, Stuart H., Premawardhena, Anuja, Bender, M.A.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174767/
https://ncbi.nlm.nih.gov/pubmed/21879898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1103070
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