Kv7.1 ion channels require a lipid to couple voltage sensing to pore opening

Voltage-gated ion channels generate dynamic ionic currents that are vital to the physiological functions of many tissues. These proteins contain separate voltage-sensing domains, which detect changes in transmembrane voltage, and pore domains, which conduct ions. Coupling of voltage sensing and pore...

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Главные авторы: Zaydman, Mark A., Silva, Jonathan R., Delaloye, Kelli, Li, Yang, Liang, Hongwu, Larsson, H. Peter, Shi, Jingyi, Cui, Jianmin
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2013
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740903/
https://ncbi.nlm.nih.gov/pubmed/23861489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305167110
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