KCNE1 Remodels the Voltage Sensor of Kv7.1 to Modulate Channel Function

The KCNE1 auxiliary subunit coassembles with the Kv7.1 channel and modulates its properties to generate the cardiac I(Ks) current. Recent biophysical evidence suggests that KCNE1 interacts with the voltage-sensing domain (VSD) of Kv7.1. To investigate the mechanism of how KCNE1 affects the VSD to al...

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Detaylı Bibliyografya
Asıl Yazarlar: Wu, Dick, Pan, Hua, Delaloye, Kelli, Cui, Jianmin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2010
Konular:
Channels and Transporters
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998620/
https://ncbi.nlm.nih.gov/pubmed/21112284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.10.018
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