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KCNE1 Remodels the Voltage Sensor of Kv7.1 to Modulate Channel Function

The KCNE1 auxiliary subunit coassembles with the Kv7.1 channel and modulates its properties to generate the cardiac I(Ks) current. Recent biophysical evidence suggests that KCNE1 interacts with the voltage-sensing domain (VSD) of Kv7.1. To investigate the mechanism of how KCNE1 affects the VSD to al...

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Autors principals: Wu, Dick, Pan, Hua, Delaloye, Kelli, Cui, Jianmin
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998620/
https://ncbi.nlm.nih.gov/pubmed/21112284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.10.018
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