Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening

In voltage-activated ion channels, voltage sensor (VSD) activation induces pore opening via VSD-pore coupling. Previous studies show that the pore in KCNQ1 channels opens when the VSD activates to both intermediate and fully activated states, resulting in the intermediate open (IO) and activated ope...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Hou, Panpan, Eldstrom, Jodene, Shi, Jingyi, Zhong, Ling, McFarland, Kelli, Gao, Yuan, Fedida, David, Cui, Jianmin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700111/
https://ncbi.nlm.nih.gov/pubmed/29167462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01911-8
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg