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Gating and Regulation of KCNQ1 and KCNQ1 + KCNE1 Channel Complexes

The IKs channel complex is formed by the co-assembly of Kv7.1 (KCNQ1), a voltage-gated potassium channel, with its β-subunit, KCNE1 and the association of numerous accessory regulatory molecules such as PIP2, calmodulin, and yotiao. As a result, the IKs potassium current shows kinetic and regulatory...

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Bibliografische gegevens
Gepubliceerd in:Front Physiol
Hoofdauteurs: Wang, Yundi, Eldstrom, Jodene, Fedida, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7287213/
https://ncbi.nlm.nih.gov/pubmed/32581825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00504
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