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State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation

The voltage-sensing domain of voltage-gated channels is comprised of four transmembrane helices (S1–S4), with conserved positively charged residues in S4 moving across the membrane in response to changes in transmembrane voltage. Although it has been shown that positive charges in S4 interact with n...

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Hlavní autoři: Wu, Dick, Delaloye, Kelli, Zaydman, Mark A., Nekouzadeh, Ali, Rudy, Yoram, Cui, Jianmin
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888051/
https://ncbi.nlm.nih.gov/pubmed/20479111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010408
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