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Conformational changes of an ion–channel during gating and emerging electrophysiologic properties: application of a computational approach to cardiac Kv7.1

Ion channels are the “building blocks” of the excitation process in excitable tissues. Despite advances in determining their molecular structure, understanding the relationship between channel protein structure and electrical excitation remains a challenge. The Kv7.1 potassium channel is an importan...

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Publicat a:Prog Biophys Mol Biol
Autors principals: Nekouzadeh, Ali, Rudy, Yoram
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955398/
https://ncbi.nlm.nih.gov/pubmed/26743208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2015.12.014
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