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Small-molecule mediated neuroprotection in an in situ model of tauopathy

Small-molecule inhibitors of neurofibrillary lesion formation may have utility for treatment of Alzheimer’s disease and certain forms of frontotemporal lobar degeneration. These lesions are composed largely of tau protein, which aggregates to form intracellular fibrils in affected neurons. Previousl...

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Autors principals: Honson, Nicolette S., Jensen, Jordan R., Abraha, Aida, Hall, Garth F., Kuret, Jeff
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740339/
https://ncbi.nlm.nih.gov/pubmed/19384600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-009-9028-y
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