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Small-molecule mediated neuroprotection in an in situ model of tauopathy

Small-molecule inhibitors of neurofibrillary lesion formation may have utility for treatment of Alzheimer’s disease and certain forms of frontotemporal lobar degeneration. These lesions are composed largely of tau protein, which aggregates to form intracellular fibrils in affected neurons. Previousl...

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Detalhes bibliográficos
Main Authors: Honson, Nicolette S., Jensen, Jordan R., Abraha, Aida, Hall, Garth F., Kuret, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740339/
https://ncbi.nlm.nih.gov/pubmed/19384600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-009-9028-y
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