A potent chemotherapeutic strategy in prostate cancer: S-(methoxytrityl)-ℒ-cysteine, a novel Eg5 inhibitor

Docetaxel-based combination chemotherapy remains the predominant treatment for castration-resistant prostate cancer. However, taxane-related drug resistance and neurotoxicity have prompted us to develop substitute treatment strategies. Eg5 (kinesin spindle protein), which is crucial for bipolar spin...

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Detalhes bibliográficos
Main Authors: Xing, Nai-Dong, Ding, Sen-Tai, Saito, Ryoichi, Nishizawa, Koji, Kobayashi, Takashi, Inoue, Takahiro, Oishi, Shinya, Fujii, Nobutaka, Lv, Jia-Jv, Ogawa, Osamu, Nishiyama, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739206/
https://ncbi.nlm.nih.gov/pubmed/21297652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2010.171
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