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A potent chemotherapeutic strategy in prostate cancer: S-(methoxytrityl)-ℒ-cysteine, a novel Eg5 inhibitor
Docetaxel-based combination chemotherapy remains the predominant treatment for castration-resistant prostate cancer. However, taxane-related drug resistance and neurotoxicity have prompted us to develop substitute treatment strategies. Eg5 (kinesin spindle protein), which is crucial for bipolar spin...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3739206/ https://ncbi.nlm.nih.gov/pubmed/21297652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2010.171 |
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