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Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy
BACKGROUND: We investigate the influence of oligomeric forms of Aß and the influence of duration of exposure on the development of tau phosphorylation. METHODS: Aβ oligomers were injected intracranially either acutely into 5 mo old rTg4510 mice and tissue collected 3 days later or chronically into 3...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3739054/ https://ncbi.nlm.nih.gov/pubmed/22796753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000337230 |
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