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Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy

BACKGROUND: We investigate the influence of oligomeric forms of Aß and the influence of duration of exposure on the development of tau phosphorylation. METHODS: Aβ oligomers were injected intracranially either acutely into 5 mo old rTg4510 mice and tissue collected 3 days later or chronically into 3...

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Detalhes bibliográficos
Main Authors: Selenica, Maj-Linda B., Brownlow, Milene, Jimenez, Jeffy P., Lee, Daniel C., Pena, Gabriela, Dickey, Chad A., Gordon, Marcia N., Morgan, Dave
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739054/
https://ncbi.nlm.nih.gov/pubmed/22796753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000337230
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