miR-196a Ameliorates Phenotypes of Huntington Disease in Cell, Transgenic Mouse, and Induced Pluripotent Stem Cell Models

Huntington disease (HD) is a dominantly inherited neurodegenerative disorder characterized by dysregulation of various genes. Recently, microRNAs (miRNAs) have been reported to be involved in this dysregulation, suggesting that manipulation of appropriate miRNA regulation may have a therapeutic bene...

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Main Authors: Cheng, Pei-Hsun, Li, Chia-Ling, Chang, Yu-Fan, Tsai, Shaw-Jeng, Lai, Yen-Yu, Chan, Anthony W.S., Chen, Chuan-Mu, Yang, Shang-Hsun
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2013
Ábhair:
Report
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738820/
https://ncbi.nlm.nih.gov/pubmed/23810380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.05.025
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