miR-196a Ameliorates Phenotypes of Huntington Disease in Cell, Transgenic Mouse, and Induced Pluripotent Stem Cell Models

Huntington disease (HD) is a dominantly inherited neurodegenerative disorder characterized by dysregulation of various genes. Recently, microRNAs (miRNAs) have been reported to be involved in this dysregulation, suggesting that manipulation of appropriate miRNA regulation may have a therapeutic bene...

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Bibliografski detalji
Glavni autori: Cheng, Pei-Hsun, Li, Chia-Ling, Chang, Yu-Fan, Tsai, Shaw-Jeng, Lai, Yen-Yu, Chan, Anthony W.S., Chen, Chuan-Mu, Yang, Shang-Hsun
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2013
Teme:
Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738820/
https://ncbi.nlm.nih.gov/pubmed/23810380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.05.025
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