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miR-196a Ameliorates Phenotypes of Huntington Disease in Cell, Transgenic Mouse, and Induced Pluripotent Stem Cell Models

Huntington disease (HD) is a dominantly inherited neurodegenerative disorder characterized by dysregulation of various genes. Recently, microRNAs (miRNAs) have been reported to be involved in this dysregulation, suggesting that manipulation of appropriate miRNA regulation may have a therapeutic bene...

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Detalhes bibliográficos
Main Authors: Cheng, Pei-Hsun, Li, Chia-Ling, Chang, Yu-Fan, Tsai, Shaw-Jeng, Lai, Yen-Yu, Chan, Anthony W.S., Chen, Chuan-Mu, Yang, Shang-Hsun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738820/
https://ncbi.nlm.nih.gov/pubmed/23810380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.05.025
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