miR-196a Ameliorates Phenotypes of Huntington Disease in Cell, Transgenic Mouse, and Induced Pluripotent Stem Cell Models

Huntington disease (HD) is a dominantly inherited neurodegenerative disorder characterized by dysregulation of various genes. Recently, microRNAs (miRNAs) have been reported to be involved in this dysregulation, suggesting that manipulation of appropriate miRNA regulation may have a therapeutic bene...

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Bibliografiska uppgifter
Huvudupphovsmän: Cheng, Pei-Hsun, Li, Chia-Ling, Chang, Yu-Fan, Tsai, Shaw-Jeng, Lai, Yen-Yu, Chan, Anthony W.S., Chen, Chuan-Mu, Yang, Shang-Hsun
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738820/
https://ncbi.nlm.nih.gov/pubmed/23810380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.05.025
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