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Ultrasensitivity in Phosphorylation-Dephosphorylation Cycles with Little Substrate

Cellular decision-making is driven by dynamic behaviours, such as the preparations for sunrise enabled by circadian rhythms and the choice of cell fates enabled by positive feedback. Such behaviours are often built upon ultrasensitive responses where a linear change in input generates a sigmoidal ch...

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Bibliografiske detaljer
Main Authors: Martins, Bruno M. C., Swain, Peter S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738489/
https://ncbi.nlm.nih.gov/pubmed/23950701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003175
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