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Kinase Inhibition Leads to Hormesis in a Dual Phosphorylation-Dephosphorylation Cycle
Many antimicrobial and anti-tumour drugs elicit hormetic responses characterised by low-dose stimulation and high-dose inhibition. While this can have profound consequences for human health, with low drug concentrations actually stimulating pathogen or tumour growth, the mechanistic understanding be...
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| Vydáno v: | PLoS Comput Biol |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5127489/ https://ncbi.nlm.nih.gov/pubmed/27898662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005216 |
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