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Kinase Inhibition Leads to Hormesis in a Dual Phosphorylation-Dephosphorylation Cycle

Many antimicrobial and anti-tumour drugs elicit hormetic responses characterised by low-dose stimulation and high-dose inhibition. While this can have profound consequences for human health, with low drug concentrations actually stimulating pathogen or tumour growth, the mechanistic understanding be...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS Comput Biol
मुख्य लेखकों: Rashkov, Peter, Barrett, Ian P., Beardmore, Robert E., Bendtsen, Claus, Gudelj, Ivana
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127489/
https://ncbi.nlm.nih.gov/pubmed/27898662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005216
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