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Allelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells
In developing B cells, the immunoglobulin heavy chain (IgH) locus is thought to move from repressive to permissive chromatin compartments to facilitate its scheduled rearrangement. In mature B cells, maintenance of allelic exclusion has been proposed to involve recruitment of the non-productive IgH...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3737562/ https://ncbi.nlm.nih.gov/pubmed/23748562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt491 |
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