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CTCF: the protein, the binding partners, the binding sites and their chromatin loops

CTCF has it all. The transcription factor binds to tens of thousands of genomic sites, some tissue-specific, others ultra-conserved. It can act as a transcriptional activator, repressor and insulator, and it can pause transcription. CTCF binds at chromatin domain boundaries, at enhancers and gene pr...

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Detalhes bibliográficos
Main Authors: Holwerda, Sjoerd Johannes Bastiaan, de Laat, Wouter
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682731/
https://ncbi.nlm.nih.gov/pubmed/23650640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0369
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