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Allelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells

In developing B cells, the immunoglobulin heavy chain (IgH) locus is thought to move from repressive to permissive chromatin compartments to facilitate its scheduled rearrangement. In mature B cells, maintenance of allelic exclusion has been proposed to involve recruitment of the non-productive IgH...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Holwerda, Sjoerd J. B., van de Werken, Harmen J. G., Ribeiro de Almeida, Claudia, Bergen, Ingrid M., de Bruijn, Marjolein J. W., Verstegen, Marjon J. A. M., Simonis, Marieke, Splinter, Erik, Wijchers, Patrick J., Hendriks, Rudi W., de Laat, Wouter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737562/
https://ncbi.nlm.nih.gov/pubmed/23748562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt491
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